Cardiovascular disease and infections are major causes for the high incidence of morbidity and mortality of patients with chronic Floor Mats (Carpet) kidney disease.Both complications are directly or indirectly associated with disturbed functions or altered apoptotic rates of polymorphonuclear leukocytes, monocytes, lymphocytes, and dendritic cells
RNF5 is an E3 ubiquitin ligase involved in various physiological processes such as protein localization and cancer progression.Recent studies have shown that RNF5 significantly inhibits antiviral innate immunity by promoting the ubiquitination and degradation of STING and MAVS, which are essential adaptor proteins, as well as their downstream signa
Alterations to the mucosal environment of the female genital tract, such as genital inflammation, have been associated with increased HIV acquisition in women.As the microbiome and hormonal contraceptives can affect vaginal mucosal immunity, we hypothesized these components may interact in the context of HIV Grip Ring susceptibility.Using previousl
Problem Management Plus (PM+) is an evidence-based intervention developed for adults impaired by distress in communities exposed to adversity.After being tested and released by the World Health Organization, a capacity building project was launched to increase the Pet Food uptake of the intervention within humanitarian settings.Humanitarian organis
Currently, international community faces bloody armed conflicts.During the operation in Syria, thousands of civilians become victims.Many other countries are suffering because they are forced to divide their homes with the waves of migrants.Every day we see violation of human rights, which are the most important values enshrined in the internationa